Liuling Yan, Professor
Dillon and Lois Hodges Professorship
Wheat Molecular Genetics and Breeding
Oklahoma State University
Department of Plant and Soil Sciences
371 Agricultural Hall
Stillwater, OK 74078-6028
Office Location:329L Noble Research Center
Phone Number: 405-744-9608
Lab Location: 346 & 347 NRC Lab Phone Number: 405-744-6928
FAX Number: 405-744-0354
The Yan lab primarily studies genetic basis and molecular mechanisms of flowering time in wheat. Wheat cultivars are classified as two general types: winter wheat requiring a period of low temperature to accelerate flowering (vernalization) and spring wheat without the requirement. Based on the qualitative vernalization requirement between the two types of wheat, three vernalization genes have been cloned VRN-1 (Yan et al. 2003. PNAS 100: 6263-6268), VRN-2 (Yan et al. 2004. Science 303: 1640-1644, a full size of research article), and VRN-3 (Yan et al. 2006. PNAS 103: 19581-19586, a cover story). VRN-1 and VRN-3 work with PPD-D1 together to regulate developmental phases from stem elongation (jointing), heading date, to physiological maturity in winter wheat (TAG 2009, Mol Breed 2011). The positional cloning of the gene for the allelic variation in quantitative vernalization requirement between semi-winter wheat requiring 3 weeks’ vernalization and strong winter wheat requiring 6 weeks’ vernalization reveals that this trait is controlled by TaVRN-A1 at the protein level (The Plant Journal 2013). The Ala180 in vrn-A1a encoded by the dominant allele for less vernalization is mutated to Val180. in vrn-A1b encoded by the recessive allele for more vernalization. With this mutation, the vrn-A1b protein showed decreased ability to bind with TaHOX1 by in vitro and in vivo protein interaction analyses.
The Yan lab also studies on resistance genes against diseases and insects in winter wheat in the southern Great Plains, including powdery mildew (Mol. Breed. 2009), leaf rust (TAG. 2010), stripe rust (Crop Sci. 2011), and Hessian fly (BMC Genomics 2013).
PhD: Plant Molecular Biology, Victoria University, Australia, 2000
MS: Wheat Applied Physiology, Yangzhou University, China, 1987
BS: Agronomy, Yangzhou University, China, 1984